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New collaboration to develop greener, more affordable anti-cancer compounds


Patients around the world could have access to more affordable cancer treatments thanks to an innovative new applied research collaboration.

̨ÍåÂãÁÄÖ±²¥ Leicester (DMU) and advanced chemical solutions specialist Fluid Science have won funding from Innovate UK to support the development of a new generation of anti-cancer compounds.

THUMB generic cancer treatment

The team will work together on developing and refining active compounds using cutting-edge green chemistry techniques, using cleaner, sustainable methods which both make the process better for the environment and reduce costs - meaning potential treatments can reach more patients.

This ambitious Knowledge Transfer Partnership (KTP) is worth just over £300,000 and brings together experts from both industry and academia. KTPs see universities team up with businesses to solve particular challenges. A KTP Associate will be recruited to work on the project supervised by the central team.

Representingare Chris Hogan, Business Manager, and Asdaq Hussain, Project and Product Manager. From DMU, the partnership includes Dr Federico Brucoli, a Senior Lecturer in Medicinal Chemistry and green chemistry expert, Dr Ketan Ruparelia, Senior NMR Technicial Instructor.

The team will be working on an open-source anti-cancer compound called DMU212 which was developed at the university by Dr Brucoli and Dr Ruparelia.

Chris Hogan, Business Manager at Fluid Science, said: "This KTP submission represents a significant strategic step for Fluid Science. Working alongside ̨ÍåÂãÁÄÖ±²¥ allows us to combine our commercial capability with deep academic research to deliver meaningful innovation. We're not just creating a product—we're building a platform for sustainable, life-saving technologies."

Asdaq Hussain, Project and Product Manager at Fluid Science, added: "This is a unique opportunity to lead a project that merges green chemistry principles with the development of critical healthcare solutions. It’s incredibly rewarding to help steer this toward real-world impact, especially when the outcome could offer more affordable treatment options globally."

Dr Federico Brucoli, Senior Medicinal Chemist, said:  “This as an exciting opportunity to jointly lead a project focussed on green chemistry applied to anticancer compounds development. The collaboration will benefit from our collective expertise of over 50 years in medicinal chemistry with deep understanding of drug development principles and strategies. The project could potentially provide more cost-effective treatment options on a global scale and result in a tangible real-world impact.”

Dr Ketan Ruparelia, Senior NMR Technician, said: “It's inspiring to see that compounds originally developed at the university are now being leveraged for a healthcare innovation project, with the aim of enhancing the quality of healthcare services. This signifies a positive step towards progress, and we are thrilled to be part of this transformative journey towards better healthcare innovation.”

Funded through Innovate UK, the KTP framework enables businesses and universities to collaborate on high-impact projects, bridging the gap between academic innovation and commercial application.

Posted on Monday 19 May 2025

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